Officers were called to Victoria tram stop at around 9.10pm last week to reports of an assault.
The victim was subsequently found with stab wounds.
He was taken to hospital and has since been discharged.
A 17-year-old, who cannot be named for legal reasons, has been charged with affray.
He will appear at Manchester City Magistrates on June 23, 2021.
A 16-year-old, who also cannot be identified for legal reasons, was charged last Friday (June 4) with S18 wounding and possession of an offensive weapon.
He appeared at Manchester City Magistrates the same day and has been remanded until July 9.
A third male has been recalled to prison.
Anyone with information should contact police on 0161 856 4409, quoting incident number 3062 of 02/05/2021, or via the LiveChat and reporting functions at: www.gmp.police.uk.
Alternatively, reports can also be made anonymously to the independent charity Crimestoppers on 0800 555 111.
