She was last seen in Manchester city centre at 3:30pm on Wednesday (December 7).
Officers are keen to make sure Melissa is safe and well.
Melissa is 5ft 5in tall with long, brown hair, and was last seen wearing grey cargo trousers and a black-and-white hoodie.
Anyone with information about Melissa’s whereabouts should contact police on 101, quoting log 1941-071222.
