At around 8.25pm emergency services responded to reports of a property fire at a property on Walkers Road, in the Hollins area of the town.
Several fire crews and police patrols attended, but sadly a person was pronounced dead at the scene.
Work is ongoing to fully establish the identification of the person.
An investigation is currently underway and specialist teams are assessing the property to establish a cause of the ignition.
Detective Inspector Roberto Dicorato, from GMP’s Oldham district, said: “A person has sadly lost their life following the fire last night, and we are working closely with partners in the fire service to establish the exact cause.
“We have not yet established the full circumstances and would ask anyone with any information, or who witnessed the fire last night, to please get in touch.
"This includes anyone with nearby CCTV or doorbell footage.”
Anyone with any information is asked to contact police via 101 or the Live Chat function at: gmp.police.uk, quoting log 3130 of 20/02/25.
Alternatively, you can contact the independent charity Crimestoppers, anonymously, on 0800 555 111.
